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热带海洋学报 ›› 2011, Vol. 30 ›› Issue (1): 124-126.doi: 10.11978/j.issn.1009-5470.2011.01.124cstr: 32234.14.j.issn.1009-5470.2011.01.124

• 海洋生物学 • 上一篇    下一篇

南海海绵Haliclona sp.的化学成分研究

李云秋1, 王宾2, 杨斌1, 黄日明1, 刘永宏1, 邹晓理3   

  1. 1. 中国科学院南海海洋研究所中科院海洋生物资源可持续利用重点实验室, 广东 广州510240; 2. 北华大学附属医院, 吉林 吉林 132001; 3. 中国科学院南海海洋研究所海洋环境工程中心, 广东 广州 510301
  • 收稿日期:2009-11-29 修回日期:2009-11-24 出版日期:2011-03-17 发布日期:2011-03-16
  • 通讯作者: 邹晓理。Tel: 020-89023181, E-mail: zxl@scsio.ac.cn
  • 作者简介:李云秋(1974—), 男, 吉林省榆树市人, 博士, 主要从事天然产物化学研究。E-mail: autumn.li@163.com
  • 基金资助:

    国家自然科学青年基金(40706046)

Study on the compounds of marine sponge Haliclona sp.

LI Yun-qiu1, WANG Bin2, YANG Bin1, HUANG Ri-ming1, LIU Yong-hong1, ZOU Xiao-li3   

  1. 1. Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, CAS, Guangzhou 510301, China; 2. Affiliated Hospital of Beihua University, Jilin 132001, China; 3. Marine Environmental Engineering Center, South China Sea Institute of Oceanology, CAS, Guangzhou 510301, China
  • Received:2009-11-29 Revised:2009-11-24 Online:2011-03-17 Published:2011-03-16
  • Contact: 邹晓理。Tel: 020-89023181, E-mail: zxl@scsio.ac.cn
  • About author:李云秋(1974—), 男, 吉林省榆树市人, 博士, 主要从事天然产物化学研究。E-mail: autumn.li@163.com
  • Supported by:

    国家自然科学青年基金(40706046)

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被引次数

8 | 4

摘要：

采用硅胶、凝胶等色谱分离方法进行分离纯化, 采用理化常数及波谱学方法鉴定结构, 研究了南海海绵Haliclona sp.的化学成分。结果从南海海绵Haliclona sp.中分离得到9个化合物, 经鉴定分别为: 正十六烷基甘油醚(Cetyl ethers of glycerol, 1)、正十二烷酸(Dodecanoic acid, 2)、2'-脱氧腺苷(2'-deoxyadenosin, 3)、尿苷(Uridine, 4)、2'-脱氧尿苷(2'-deoxyuridine, 5)、2'-脱氧胸苷(2'-deoxythymidine, 6)、α-乙基葡萄糖苷(α-ethyl glucoside, 7)、对羟基苯乙胺(Tyramine,8)、异戊胺(Isopentylamine, 9)。化合物4、5、7和9为首次从该属中分离得到。

关键词: 海绵, Haliclona sp., 化学成分

Abstract:

The objective is to study the compounds from the marine sponge Haliclona sp. The compounds were isolated and purified by various column chromatography methods, and their structures were identified by physico-chemical properties and spectral analysis. Nine compounds were isolated and identified as Cetyl ethers of glycerol (1), Dodecanoic acid (2), 2'-deoxyadenosin (3), Uridine (4), 2'-deoxyuridine (5), 2'-deoxythymidine (6), α-ethyl glucoside (7), Tyramine (8), Isopen-tylamine (9). Note that compounds 4, 5, 7, and 9 were isolated from marine sponge Haliclona sp. for the first time.

Key words: marine sponge, Haliclona sp., chemical constituents