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    Research status and development trends of natural products from marine microorganisms
    MA Lili, TIAN Xinpeng, LI Guiju, ZHAO Yanqiang, YIN Jianping
    Journal of Tropical Oceanography    2021, 40 (5): 134-146.   DOI: 10.11978/2020104
    Abstract2573)   HTML1691)    PDF (3887KB)(1588)      

    Because of their unique habitat and metabolic pathways, marine microorganisms can produce a variety of bioactive substances with novel structures and functions, which make natural products from these marine microorganisms become a research hotspot of new marine drugs. Combining the methods and perspectives of bibliometrics, we review in this paper the research status of natural products from marine fungi and marine bacteria, the artificial synthesis of natural products of marine microorganisms, the biological activity and druggability evaluation of natural products from marine microorganisms, to clarify the current status and development trend of natural products from marine microorganisms.

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