收稿日期: 2009-11-29
修回日期: 2009-11-24
网络出版日期: 2011-03-16
基金资助
国家自然科学青年基金(40706046)
Study on the compounds of marine sponge Haliclona sp.
Received date: 2009-11-29
Revised date: 2009-11-24
Online published: 2011-03-16
Supported by
国家自然科学青年基金(40706046)
采用硅胶、凝胶等色谱分离方法进行分离纯化, 采用理化常数及波谱学方法鉴定结构, 研究了南海海绵Haliclona sp.的化学成分。结果从南海海绵Haliclona sp.中分离得到9个化合物, 经鉴定分别为: 正十六烷基甘油醚(Cetyl ethers of glycerol, 1)、正十二烷酸(Dodecanoic acid, 2)、2'-脱氧腺苷(2'-deoxyadenosin, 3)、尿苷(Uridine, 4)、2'-脱氧尿苷(2'-deoxyuridine, 5)、2'-脱氧胸苷(2'-deoxythymidine, 6)、α-乙基葡萄糖苷(α-ethyl glucoside, 7)、对羟基苯乙胺(Tyramine,8)、异戊胺(Isopentylamine, 9)。化合物4、5、7和9为首次从该属中分离得到。
关键词： 海绵; Haliclona sp.; 化学成分
李云秋,王宾,杨斌,黄日明,刘永宏,邹晓理 . 南海海绵Haliclona sp.的化学成分研究[J]. 热带海洋学报, 2011 , 30(1) : 124 -126 . DOI: 10.11978/j.issn.1009-5470.2011.01.124
The objective is to study the compounds from the marine sponge Haliclona sp. The compounds were isolated and purified by various column chromatography methods, and their structures were identified by physico-chemical properties and spectral analysis. Nine compounds were isolated and identified as Cetyl ethers of glycerol (1), Dodecanoic acid (2), 2'-deoxyadenosin (3), Uridine (4), 2'-deoxyuridine (5), 2'-deoxythymidine (6), α-ethyl glucoside (7), Tyramine (8), Isopen-tylamine (9). Note that compounds 4, 5, 7, and 9 were isolated from marine sponge Haliclona sp. for the first time.
Key words： marine sponge; Haliclona sp.; chemical constituents
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