收稿日期: 2009-12-31
修回日期: 2010-04-11
网络出版日期: 2011-03-16
基金资助
国家自然科学基金(40706046, 30973679)
Pregnane steroids from a gorgonian Menella sp. in South China Sea
Received date: 2009-12-31
Revised date: 2010-04-11
Online published: 2011-03-16
Supported by
国家自然科学基金(40706046, 30973679)
从南海小月柳珊瑚Menella sp. 石油醚萃取部位中分离得到7个孕甾烷类化合物, 通过波谱分析并与文献对照, 其结构分别鉴定为 3α-羟基-5β-孕甾-20-酮(1), 3β-羟基-5α-孕甾-20-酮(2), 3β-羟基-孕甾-5-烯-20-酮(3), 5β-孕甾-3, 20-二酮(4), 5α-孕甾-3, 20-二酮(5), 孕甾-4-烯-3, 20-二酮(6), 孕甾-1, 4-二烯-3, 20-二酮(7); 除化合物2外其他化合物都为首次从该属柳珊瑚中分离得到, 其中化合物7是首次报道其核磁数据。
关键词： 小月柳珊瑚Menella sp.; 孕甾烷; 甾体; 化学成分; 结构鉴定
柴兴云,胡静,黄晖,雷辉,陈显强,李云秋,孙见凡,董光,刘永宏,刘学东 . 小月柳珊瑚中孕甾烷类的化学成分研究[J]. 热带海洋学报, 2011 , 30(1) : 127 -130 . DOI: 10.11978/j.issn.1009-5470.2011.01.127
Seven pregnane steroids were isolated from the petroleum ether extracts of a South China Sea gorgonian Menella sp. collected in the Sanya Bay. By means of spectroscopic analysis and comparison with literatures, their structures were identi-fied as 3α-hydroxy-5β-pregnan-20-one (1), 3β-hydroxy-5α-pregnan-20-one (2), 3β-hydroxy-pregnan-5-en-20-one (3), 5β-pregnan-3, 20-dione (4), 5α-pregnan-3, 20-dione (5), pregnan-4-en-3, 20-dione (6), and pregnan-1, 4-dien-3, 20-dione (7), respectively. All compounds except compound 2 were isolated from this genus for the first time, and the NMR data of com-pound 7 was reported for the first time.
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