Marine biology

Study on the compounds of marine sponge Haliclona sp.

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  • 1. Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, CAS, Guangzhou 510301, China; 2. Affiliated Hospital of Beihua University, Jilin 132001, China; 3. Marine Environmental Engineering Center, South China Sea Institute of Oceanology, CAS, Guangzhou 510301, China
李云秋(1974—), 男, 吉林省榆树市人, 博士, 主要从事天然产物化学研究。E-mail: autumn.li@163.com

Received date: 2009-11-29

  Revised date: 2009-11-24

  Online published: 2011-03-16

Supported by

国家自然科学青年基金(40706046)

Abstract

The objective is to study the compounds from the marine sponge Haliclona sp. The compounds were isolated and purified by various column chromatography methods, and their structures were identified by physico-chemical properties and spectral analysis. Nine compounds were isolated and identified as Cetyl ethers of glycerol (1), Dodecanoic acid (2), 2'-deoxyadenosin (3), Uridine (4), 2'-deoxyuridine (5), 2'-deoxythymidine (6), α-ethyl glucoside (7), Tyramine (8), Isopen-tylamine (9). Note that compounds 4, 5, 7, and 9 were isolated from marine sponge Haliclona sp. for the first time.

Cite this article

LI Yun-qiu,WANG Bin,YANG Bin,HUANG Ri-ming,LIU Yong-hong,ZOU Xiao-li . Study on the compounds of marine sponge Haliclona sp.[J]. Journal of Tropical Oceanography, 2011 , 30(1) : 124 -126 . DOI: 10.11978/j.issn.1009-5470.2011.01.124

References

[1]       , 相宇, 黄卫华, . 日本医蛭化学成分研究[J]. 海峡药学, 2009, 21(5): 75-77.

[2]       闫兴国, 保全, 周渊, . 三角叶荨麻根的化学成分[J]. 沈阳药科大学学报, 2008, 25(11): 880-882.

[3]       杨顺, 刘锡葵. 竹叶菜中的核苷类化学成分[J]. 中国天然药物, 2003, 1(4): 196-198.

[4]       邓雁如, 丁兰, 武水仙, . 紫花野芝麻化学成分研究Ⅱ[J]. 中国中药杂志, 2005, 30(4): 272-274.

[5]       刘昌达, 陈靖, 王金辉, 西洋参花蕾中非皂苷类化学成分[J]. 沈阳药科大学学报, 2009, 26(8): 626-628.

[6]       PARAMASHIVAPPA R, PHANI K P, SUBBA R P V, et al. Simple and efficient method for the synthesis of 2', 3'-didehydro-3'-deoxythymidine (d4T)[J]. Tetrahedron Letters, 2003, 44 (5): 1003-1005.

[7]       于嘉陵, 严小红, 惠欣, . 桂山厚丛柳珊瑚化学成分的研究() [J]. 天然产物研究与开发, 2004, 16(2): 118-120.

[8]       王金兰, 李灵, 贺礼东, .牵牛全草的化学成分研究[J]. 天然产物研究与开发, 2007, 19: 427-429.

[9]       ROUSH W R, HERNANDEZ A A, McKERROW J H, et al. Design, synthesis and evaluation of D-homophenylalanyl epoxysuccinate inhibitors of the trypanosomal cysteine protease cruzain[J]. Tetrahedron, 2000, 56: 9747-9762.

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