The authors have summarized a set of rules for choosing and verifying the main acquisition parameters in marine seismic exploration based on previous experiences of long-term practice. Firstly, an analysis is carried out for the selected area to establish a representative seismogeological model using various seismic and geologic information. Considering the current devices’ performances and options，they use a professional simulation software, Nucleus 6.2, to compute source parameters and to compare the response to various combinations of acquisition parameters, in order to choose a combination that is best adaptive to certain task. An actual exploration test is also carried out to verify the parameters’ combination chosen from the simulation test. Finally, the authors select the optimum Parameters’ combination and obtain quality data for production.