深海冷泉来源真菌Talaromyces helicus SCSIO41311中聚酮类化学成分研究

doi:10.11978/2021168

Journal of Tropical Oceanography ›› 2022, Vol. 41 ›› Issue (5): 117-120.doi: 10.11978/2021168CSTR: 32234.14.2021168

• Marine Biology • Previous Articles Next Articles

Study on the polyketides from a cold-seep-derived Talaromyces helicus SCSIO41311

CONG Mengjing¹^,³(), HU Yiwei¹^,³, ZHAO Kai¹, ZHANG Xiaoyong², LIU Yonghong¹^,³, WANG Junfeng¹^,³()

1. CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
2. College of Marine Science, South China Agricultural University, Guangzhou 510642, China
3. University of the Chinese Academy of Sciences, Beijing 100049, China

Received:2021-12-01 Revised:2021-12-17 Online:2022-09-10 Published:2021-12-21
Contact: WANG Junfeng E-mail:congmengjing@mails.ucas.ac.cn;wangjunfeng@scsio.ac.cn
Supported by:
Finance Science and Technology Project of Hainan Province(ZDKJ202018);National Natural Science Foundation of China(41776169);Guangdong Basic and Applied Basic Research Foundation(2021A1515011523)

Abstract

Abstract:

In this study, we aim to investigate the secondary metabolites of polyketides from the South China Sea cold-seep-derived Talaromyces helicus SCSIO41311. The polyketides were isolated by normal phase silica gel column chromatography, reverse phase silica gel column chromatography, Sephadex LH-20, high-performance liquid chromatography (HPLC) and thin layer chromatography (TLC). The structures of compounds were identified by nuclear magnetic resonance spectrum (NMR), mass spectrometry (MS) and literature analysis. Seven polyketides were obtained and elucidated as follows: desmethylsulochrin (1), sulochrin (2), monomethylsulochrin (3), circinophoric acid (4), dimethyl 2,3-dimethylosoate (5), endocrocin (6) and 1-methyl emodin (7). All compounds were obtained for the first time from deep sea cold-seep. NMR data of 1 was firstly reported.

Key words: deep sea, cold-seep, polyketides, structure identification

CLC Number:

P735.4

CONG Mengjing, HU Yiwei, ZHAO Kai, ZHANG Xiaoyong, LIU Yonghong, WANG Junfeng. Study on the polyketides from a cold-seep-derived Talaromyces helicus SCSIO41311[J].Journal of Tropical Oceanography, 2022, 41(5): 117-120.

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References 13

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Study on the polyketides from a cold-seep-derived Talaromyces helicus SCSIO41311

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