Journal of Tropical Oceanography ›› 2017, Vol. 36 ›› Issue (1): 106-113.doi: 10.11978/2016001CSTR: 32234.14.2016001

• Orginal Article • Previous Articles    

Residual antibiotics in the Nansha aquaculture area of Guangzhou

Qinwei HAO1,3(), Xiangrong XU1(), Hui CHEN1,3, Shan LIU1,3, Jun CHEN2,3, Shuangshuang LIU2,3, Guangguo YING2   

  1. 1. Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
    2. State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China
    3. University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2016-01-05 Revised:2016-02-03 Online:2017-01-18 Published:2017-01-19
  • Supported by:
    National Natural Science Foundation of China (51378488);Guangzhou Science and Technology Plan Projects (201510010031)

Abstract:

The residual antibiotics have caused public concerns with the rapid development of aquaculture, due to their adverse effects on aquatic ecosystems and human health. A method named solid-phase extraction-rapid resolution liquid chromatography-tandem mass spectrometry (SPE-RRLC-MS/MS) was used to determine the occurrence and bioaccumulation of 35 antibiotics (14 sulfonamides, 10 fluoroquinolones, 6 macrolides, 2 tetracyclines and 3 others) in environmental matrix and different tissues of fish in the Nansha aquaculture area of Guangzhou. Twelve antibiotics were detected in water, suspended particulates, sediments and feeds, with maximum concentrations of 60.76 µg·L-1 (Erythromycin-H2O), 1691 ng·g-1 (Monensin), 2.41 ng·g-1 (Enrofloxacin) and 74.96 ng·g-1 (Enrofloxacin), respectively. Eleven antibiotics were detected in fish plasma, livers and muscle, with maximum concentrations of 33.52 µg·L-1 (Erythromycin-H2O), 199 ng·g-1 (Norfloxacin) and 22.30 ng·g-1 (Norfloxacin), respectively. The values of bioaccumulation factors (BAFs) for the detected antibiotics in fish plasma, livers, and muscle were in the ranges of 147~336, 7~8891 and 8~16, respectively, indicating a different bioaccumulation capacity for different tissues. Human health risk assessment based on potential fish consumption indicated that residues of antibiotics in these aquatic products do not pose risks to consumers’ health. The current study is of great significance in ensuring the safety of aquatic products in Guangzhou, promoting the sustainable development of aquaculture and improving the regulation on residual antibiotics for environmental protection agencies.

Key words: aquaculture, antibiotics, fish tissues, bioaccumulation, health risk