Fig. 1

The phylogenetic tree of strain SG49"

Tab. 1

The abundance of intracellular and extracellular metabolites from SG49"

Fig. 2

The data quality analysis of all metabolites. (a) The quality evaluation curve of QC samples. Dashed lines indicate pre-pretreatment data and solid lines represent post-pretreatment data. (b) The heat map of sample correlations"

Fig. 3

The OPLS-DA plot of metabolites in SG49 intracellular and extracellular groups. (a) OPLA-DA analysis of intracellular and extracellular groups in positive ion mode; (b) OPLA-DA analysis of intracellular and extracellular groups in negative ion mode; (c) permutation testing for OPLA-DA analysis in positive ion mode; (d) permutation testing for OPLA-DA analysis in negative ion mode"

Fig. 4

The annotation and enrichment analysis of metabolites. (a) Unique metabolites of intracellular group at superclass level of HMDB database; (b) enrichment analysis diagram of KEGG pathway of unique metabolites in intracellular group; (c) unique metabolites of extracellular group at superclass level of HMDB database; (d) enrichment analysis diagram of KEGG pathway of unique metabolites in extracellular groups; (e) Venn analysis chart comparing samples from intracellular and extracellular groups"

Fig. 5

Volcanic map of differential metabolite analysis of SG49 intracellular and extracellular groups (left panel) and 16 significantly different metabolites between intracellular and extracellular groups (right panel)"

Fig. 6

KEGG functional pathway of intracellular and extracellular unique metabolites. (a) KEGG pathway of unique metabolites in intracellular group; (b) KEGG pathway of unique metabolites in extracellular group; (c) the abundance of other secondary metabolite biosynthesis in intracellular group; (d) the abundance of other secondary metabolite biosynthesis in extracellular group"