中国南海软珊瑚附生真菌Acremonium sp. SCSIO41216的次级代谢产物研究

doi:10.11978/2020103

Abstract

Abstract:

The rice fermentation products of the soft coral-derived fungus Acremonium sp. SCSIO41216 from the South China Sea were isolated and purified by silica gel column, medium pressure preparative liquid chromatography (MPLC), ostade-cylsilane (ODS), and semipreparative high Performance Liquid Chromatography (HPLC). The structures of the isolated compounds were identified by nuclear magnetic resonance (NMR)and mass spectrum (MS), and compared with the published data. Seven known compounds were obtained and identified as fischexanthone (1), sydowinin A (2), (22E)-5α,8α- epidioxyergosta-6,22-dien-3β-ol (3), 16-deacetylfusidic acid lactone (4), cyclo-((S)-Pro-(R)-Leu) (5), cyclo-(S)-Pro-8- hydroxy-(R)-Ile (6), and cyclo (L)-Pro-(L)-Phe (7). Compounds 1-7 were isolated from Acremonium sp. derived from marine soft coral for the first time.

Key words: South China Sea, soft coral, Acremonium sp., secondary metabolites

CLC Number:

R282.77

ZHANG Han, TAN Yanhong, YANG Bin, LIU Yonghong, LI Yunqiu. Study on the secondary metabolites from the South China Sea soft coral-derived fungus Acremonium sp. SCSIO41216[J].Journal of Tropical Oceanography, 2021, 40(6): 135-139.

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Study on the secondary metabolites from the South China Sea soft coral-derived fungus Acremonium sp. SCSIO41216

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