柳珊瑚Leptogorgia rigida中甾体类成分研究

doi:10.11978/2018125

Abstract

Abstract:

Research was carried out on novel secondary metabolites from Leptogorgia rigida collected from the South China Sea. The secondary metabolites were isolated by silica gel column chromatography, ODS, Sephadex LH-20, thin layer chromatography, and high performance liquid chromatography (HPLC). The structures of compounds were identified by nuclear magnetic resonance spectrum (NMR), mass spectrum (MS), and literature analysis. Eight sterols were obtained and elucidated as follows: 3β, 6β, 11-trihydroxy-24-methyl-5α-chloest-9, 11-seco-7-en-9-one (1); 3β, 6α, 11-trihydroxy-24- methyl-5α-chloest-9, 11-seco-7-en-9-one (2); 3β, 6α, 11-tri- hydroxy-5α-chloest-9, 11-seco-7, 22(E)- dien-9-one (3); pregnan- 4-en-3, 20-dione (4); 5α-pregnan-3, 20-dione (5); 3β-hydroxy- pregnan-5-en-20-dione (6); 3β-hydroxy-5α-pregnan-20-one (7); and Gorgosterol (8). All the sterols were first obtained from Leptogorgia rigida.

Key words: Leptogorgia rigida, secondary metabolites, secosterols, identification

Xiji XIAO,Yun DENG,Lufeng XIE,Qi ZHANG,Xia WEI,Xin YU,Cuixian ZHANG. Research on Sterols from Leptogorgia rigida[J].Journal of Tropical Oceanography, 2019, 38(4): 64-69.

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References 25

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Research on Sterols from Leptogorgia rigida

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