中国南海软珊瑚真菌Eupenicillium sp. DX-SER3 (KC871024)的次级代谢产物研究

doi:10.11978/2018072

Abstract

Abstract:

We aim to study the secondary metabolites from the South China Sea soft coral-derived fungus Eupenicillium sp. DX-SER3 (KC871024). The rice fermentation products of the strain were purified by comprehensive chromatography methods of silica gel column, medium pressure preparative liquid chromatography (MPLC), ostade-cylsilane (ODS), and semi- preparative HPLC. The compounds’ structures were identified by nuclear magnetic resonance spectroscopy, mass spectroscopy, and comparison with the reported data. Five known compounds were obtained and identified as helvolic acid, β-adenosine, 2'-deoxythymidine, N-acyltryptamine, and p-hydroxybenzaldehyde. The high yield of the helvolic acid indicates that this strain has the potential to develop an engineered strain of this kind of compound. Helvolic acid was also tested for the activities of phytopathogenic fungus, and the result was not clear.

Key words: South China Sea, soft coral, Eupenicillium sp., secondary metabolites

CLC Number:

P735.4

Yanhong TAN, Jixing LI, Xiuping LIN, Bin YANG, Yonghong LIU, Yunqiu LI. Study on the secondary metabolites from the South China Sea soft coral-derived fungus Eupenicillium sp. DX-SER3 (KC871024)[J].Journal of Tropical Oceanography, 2019, 38(2): 43-47.

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References 18

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Study on the secondary metabolites from the South China Sea soft coral-derived fungus Eupenicillium sp. DX-SER3 (KC871024)

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